1. Original tumor
neuroblastoma cell line, established, published in Cancer 1997;79:2036-44
1. Original tumor
differentiating, low cellularity
undifferentiated, high cellularity
2. DNA ploidy
original tumor D.I.=1.55
established cell line D.I.=1.06
3.cell morphology
Giemsa staining
Electron microscopy
4.N-myc amplification
N-myc amplification
DIG-labeled probe (2p23-24)